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Root Meridian Home About Services How It Works Risks & Safety Treatment Evidence Contact Independent resource · safety first Ibogaine Therapy Ibogaine therapy is the use of the psychoactive alkaloid ibogaine in structured, medically supervised sessions. It sits at the intersection of substance use, trauma, emerging research, serious safety questions, and evolving policy. Root Meridian is an independent information resource. This page does not promote treatment or replace individualized medical or legal guidance. A clear starting point What the term means Ibogaine is a naturally occurring indole alkaloid found in the root bark of Tabernanthe iboga , a shrub native to Central and West Africa. Its cultural context includes Bwiti spiritual ceremonies, and that history deserves care rather than simplification. The Berkeley Center for the Science of Psychedelics overview of ibogaine describes both its origins and the questions that surround contemporary use. At low doses, ibogaine may act as a stimulant. At higher doses, it can produce a prolonged oneirogenic, or “waking dream,” state that may last 24–36 hours or longer. In practice, ibogaine therapy generally refers to a therapeutic-dose session paired with pre-treatment screening, continuous monitoring, recovery time, and follow-up integration. A powerful experience is not the same thing as an established treatment. The care pathway Questions that matter before any conversation Ibogaine is often discussed in relation to opioid use disorder and other substance use disorders, as well as PTSD, depression, and traumatic brain injury. Those areas of interest should not obscure the need for careful eligibility assessment, monitoring, and aftercare. 01 Screening first Cardiac history, medication interactions, substance use, and other health factors are central to risk assessment. Ibogaine has known cardiac concerns. 02 Monitoring matters A single high-dose session can be prolonged and intense. Structured settings emphasize

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